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KMID : 0359720130310040270
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Journal of the Korean Neurological Association
2013 Volume.31 No. 4 p.270 ~ p.272
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Cyclosporine-Induced Posterior Reversible Leukoencephalopathy Syndrome With Reduced Cerebral Perfusion
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Kang Tae-Ho
Cho Kee-Young
Sung Sang-Min
Jung Dae-Soo
Park Kyu-Hyun
Cho Han-Jin
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Abstract
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Posterior reversible leukoencephalopathy syndrome (PRLS) is a disorder that is characterized by reversible white-matter edema affecting the posterior regions of the brain. There are rare cases in which cyclosporine has been cited as a medication responsible for PRLS, which causes hypoperfused ischemia by endothelial injury and vasoconstriction, with resultant vasogenic edema. A PRLS patient in whom the condition was induced by cyclosporine is described herein. Perfusion computed tomography revealed a clinically relevant hypoperfused area, including the zones of vasogenic edema
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KEYWORD
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Posterior reversible leukoencephalopathy syndrome, Cyclosporine, Perfusion computed tomography
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